Resources

Dive into the latest research insights, read up on new analysis tools, download case studies and white papers, and more.

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Silvin Gol & Evelien Schaafsma, Ph.D.

Foundation Models for Biomedical Research

Foundation models use advanced machine learning algorithms and massive training datasets to infer patterns and make predictions from a variety of data types. These models are enabling biomedical scientists to probe increasingly complex research questions.

Silvin Golumbeanu & Andrew Wight, Ph.D.,

Geneformer: Powering Drug Target Discovery with Network Biology

Geneformer is a tool developed by Theodoris et al. (Nature 2023) to predict tissue-specific gene network dynamics from single-cell transcriptomic data.

Silvin Gol & Evelien Schaafsma Ph.D.

Transposons: Jumping from the Lab to the Clinic

Transposons are genetic elements that can move locations in the genome. As relatively straightforward systems for gene editing, transposons have enabled the development of many new research and clinical tools.

Silvin Gol & Evelien Schaafsma Ph.D.

Spatial Transcriptomics: Applications, Methods, & Challenges

Spatial transcriptomics approaches are used to measure gene expression in the spatial context of a tissue sample. While these techniques hold tremendous promise for many research fields, there are still analysis and interpretation challenges to resolve.

Silvin Gol

Lipid Rafts in Disease & Therapeutics

Lipid rafts are components of the cell membrane formed by tightly-packed lipids, cholesterol, and proteins. They play an integral role in many cellular processes, making them a topic of interest for drug development and disease research.

Interview conducted by Siobhan Keegan, representing Watershed Bio.

Science Chat with Dr. Daria Shlyueva

Dr. Daria Shlyueva is a Senior Scientist at Novo Nordisk. We spoke to Dr. Shlyueva about the fundamentals of a scientific education, the importance of metadata in research, and much more.

Interview conducted by Blake Gowen, representing Watershed Bio.

Science Chat with Dr. Andrew Spencley

Dr. Andrew Spencley is a Genome Editing Scientist at Novo Nordisk. We spoke to Dr. Spencley about navigating the scientific process from bench to analysis, the importance of mentorship, and more.

Interview conducted by Siobhan Keegan, representing Watershed Bio.

Science Chat with Dr. Alisa Vershinina

Dr. Alisa Vershinina is a Senior Scientist in Bioinformatics at SalioGen Therapeutics. We spoke to Dr. Vershinina about her fascinating background in paleogenomics and her journey from entomology in Russia to biotech in the U.S.

Interview conducted by Siobhan Keegan, representing Watershed Bio.

Science Chat with Dr. Paola Moreno-Roman

In our new Science Chat, we speak to professor and STEM outreach expert Dr. Paola Moreno-Roman about how her communities in both her native Peru and the U.S. shaped her research career & advocacy work.

Silvin Golumbeanu

CPTAC and the Impact of Proteogenomics on Cancer Research

By applying novel proteogenomic data analysis tools to datasets like the Clinical Proteomic Tumor Analysis Consortium (CPTAC), researchers are rapidly advancing our understanding of cancer.

Interview conducted by Siobhan Keegan, representing Watershed Bio.

Science Chat with Dr. Mallori Upshaw

Dr. Mallori Upshaw is the Director of Business Insights and Strategy at AstraZeneca, focusing on COVID-19 vaccines and immunotherapies. We spoke with Dr. Upshaw about her unique scientific journey and her experiences as a Black woman in STEM.

Silvin Golumbeanu, Naba Naufer, Ph.D. & Stefanie Morgan, Ph.D.

Large Language Models in Biology

Popularly used in chat interfaces like ChatGPT, Large Language Models (LLMs) are also being used to decode the various languages of biology.

Interview conducted by Siobhan Keegan, representing Watershed Bio.

Science Chat with Dr. Miranda Stratton

Check out our new series, “Science Chats”, with our first guest - Dr. Miranda Stratton!

Naba Naufer, Ph.D.

AlphaFold: Applications for Biomedical Research

AlphaFold2 predictions have been used to probe questions at the heart of biomedical research, like how to design superior drugs, and how protein structure impacts disease.

Silvin Golumbeanu

Nobel Prize Day 2023: The Road to mRNA Vaccines

Drs. Karikó and Weissman’s research into mRNA and the immune system enabled the rapid development of vaccines against the SARS-CoV-2 virus.

Argus Athanas, Ph.D.

Using gnomAD to Drive Insights in Precision Medicine

The Genome Aggregation Database (gnomAD) is a collaborative effort to make data from large-scale sequencing projects publicly available for scientific use. Learn how to leverage the latest updates to the database, including new data from more than 700k individuals.

Stefanie Morgan, Ph.D.

Leveraging Public Datasets for Drug Discovery

The amount of public biological data available to researchers has exploded – but garnering insights requires appropriate infrastructure, expertise, and resources.

Stefanie Morgan, Ph.D.

Cell Painting with Watershed

The JUMP-Cell Painting Consortium combines images from nearly 120,000 chemical and 18,000 genetic perturbations with high-dimensional data analytics to streamline the drug discovery process.

Tommy Tang, Ph.D.

Variant Calling for Disease-Causing Mutations: The state-of-art process

Explore important considerations for effective and accurate variant calling in WGS/WES data.

Tommy Tang, Ph.D.

Unlock the Power of Genomics Data Analysis: Watershed's Seamless Cloud Computing Solution

Dr. Tommy Tang reviews the challenges with cloud computing in biotech, with an emphasis on concerns facing startups.

Watershed Informatics: The First Omics Bench for Modern Researchers

Watershed was founded to empower the world’s scientists to transform today’s big data into tomorrow’s precision medicines.

IRGQ: A novel protein target for cancer therapeutics

Watch our webinar with protein and cancer biology expert Dr. Vinay Eapen to learn about IRGQ, a novel protein target for cancer therapeutics.

Bugs and Junk: Transforming data from emerging -omics fields into novel therapeutics

Watch our webinar with computational biologist Dr. Liyang Diao to learn how novel bioinformatics approaches are unlocking the therapeutic potential of emerging research areas.

The limits of dimensionality reduction tools for single-cell analysis

Learn how to visualize single-cell data and interrogate the outputs of dimensionality reduction tools like t-SNE and uMAP.

Cytometry in the -Omics Era for All

Learn how to overcome computational and technical barriers in flow cytometry data analysis and access cytomics insights with Dr. Andrew Wight.

The Future of Human Gene Editing

Coming on 3/7, Watershed has the honor of hosting a webinar by groundbreaking genetics researcher Nancy L. Craig.

Advances in Big Data for Immuno-Oncology

Watch our webinar with cancer researcher Dr. Michelle Atallah to learn about the latest challenges and opportunities towards realizing the potential of big data in immunology and proteomics.

March 21, 2024

Dr. Stefanie Morgan's SciMed Podcast

Hear our own Stefanie Morgan's discussion with Adam Stasio and SciMed on Streamlining Bioinformatics.

January 29, 2024

New Automation Features for Streamlined Data Processing and Analysis

Our new workflow automation features help you accelerate high-volume data processing from upload to output.

December 29, 2023

Watershed's 2023 Year In Review

From closing Series A to processing over a petabyte of data, 2023 was a pivotal year in Watershed's growth. Check out this collection of some of our top highlights from this year.

April 9, 2023

Watershed Secures $14.5M Series A to Help Scientists Unlock Multi-Omic Insights for Drug Discovery

Financing will accelerate commercial roll-out of the company's cloud-based platform that provides a unified workspace for data-intensive biomedical research accessible by both biologists and bioinformaticians

Accelerating Multi-omics Analysis

Download our white paper to learn how Watershed is revolutionizing the use of big data in biology.

Developing a Next-Generation Gene Editing Platform with Watershed

A privately-held biotechnology company is developing a new category of gene therapies.

How Violet Therapeutics Scaled Their Target Discovery Platform with Watershed

Violet Therapeutics is a pre-clinical stage company leveraging their first-in-class platform, based on RABID-seq technology, to map and mine the cellular connectome at scale.